半空之中，漂浮着闪烁着多彩光芒的“知识之箱”，那里面藏着数不尽的世界、时间和人类。杜娅尔（种田梨沙 配音）与多萝茜（佐仓绫音 配音）穿梭于“知识之箱”之中，与侵蚀各个世界的病毒作战。凡是被病毒污染的世界，必须尽快予以消除。
An affluent medical professor, Komiya, and his bossy wife, Tokio, are to look after Setsuko, their high-spirited niece from Osaka. Setsuko is a liberated woman who does what she wants, including smoking, even though she is a minor. On Saturday, the professor does not feel like going to his weekend golf game, but his wife packs him off anyway. So he leaves his bag at the apartment of his student Okada, and goes to a bar with a friend. Setsuko traces him there, and insists that he take her to a geisha house. When she gets rather tipsy, the professor calls Okada to take her home, while he sleeps at Okada's. The wife becomes suspicious of Setsuko when she sees Okada bringing her home, and also of her husband when she discovers that he did not go golfing.
